Numerical Analysis of Airway Mucus Clearance Effectiveness Using Assisted Coughing Techniques
نویسندگان
چکیده
منابع مشابه
Role of simulated repetitive coughing in mucus clearance.
The role of repetitive simulated coughing on the clearance of gel mucus simulant was investigated in vitro, by using a simulated cough machine. The repetition of cough induced a significant increase (p less than 0.01) in mucus simulant clearance (139.3 +/- 78.7 mm) in comparison to a single cough (24.9 +/- 27.5 mm). Moreover, the increase in frequency of the repetitive coughing induced a marked...
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Airway surface liquid is comprised of mucus and an underlying, watery periciliary liquid (PCL). In contrast to the well-described axial transport of mucus along airway surfaces via ciliary action, theoretical analyses predict that the PCL is nearly stationary. Conventional and confocal microscopy of fluorescent microspheres and photoactivated fluorescent dyes were used with well-differentiated ...
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Whilst the trials quoted in the Cochrane reviews [5–7] provide various degrees of quality of evidence, the key information that is missing from these studies is an understanding of the physiological principles by which these different techniques work. Physiologically, the techniques need to do the following. 1) Increase absolute peak expiratory flow (PEF) to move secretions towards the orophary...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2020
ISSN: 2045-2322
DOI: 10.1038/s41598-020-58922-7